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fopen(/var/www/html/sfatulmedicului.ro/magazin_plafar/system/cache/cache.currency.1414795154): failed to open stream: No such file or directory in /var/www/html/sfatulmedicului.ro/magazin_plafar/system/library/cache.php on line 36Warning: fwrite(): supplied argument is not a valid stream resource in /var/www/html/sfatulmedicului.ro/magazin_plafar/system/library/cache.php on line 38Warning: fclose(): supplied argument is not a valid stream resource in /var/www/html/sfatulmedicului.ro/magazin_plafar/system/library/cache.php on line 40 zinat prospect
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  • Ketek

    Compozitie
    Ketek este un medicament care contine substanta activa telitromicina. Este disponibil sub forma de comprimate alungite de culoare portocalie care contin 400 mg de telitromicina.

    Actiune terapeutica
    Substanta activa continuta de Ketek, telitromicina, este un antibiotic care apartine clasei de „ketolide”. Acestea sunt strans inrudite cu macrolidele. Telitromicina actioneaza prin blocarea ribozomilor bacterieni (locurile din celula in care se produc proteinele), inhiband dezvoltarea bacteriei. Lista completa a bacteriilor impotriva carora Ketek este activ se gaseste in Rezumatul caracteristicilor produsului (care face parte, de asemenea, din EPAR).

    Indicatii
    Ketek este utilizat pentru tratarea pacientilor adulti cu pneumonie comunitara usoara sau moderata (infectie la nivel pulmonar care este dobandita in afara spitalului) De asemenea, medicamentul se foloseste pentru tratarea adultilor care prezinta urmatoarele infectii, atunci cand acestea sunt cauzate de bacterii care sunt sau pot fi rezistente (insensibile) la betalactamine sau la macrolide (tipuri de antibiotice):
    - acutizarea (reactivarea) bronsitei cronice (inflamatia de lunga durata a cailor respiratorii pulmonare);
    - sinuzita acuta (inflamatia recenta a sinusurilor, cavitatile pline cu aer de la nivelul oaselor din jurul nasului si ochilor).
    De asemenea, Ketek se foloseste pentru tratarea pacientilor in varsta de 12 ani sau peste care prezinta amigdalite sau faringite (infectii ale amigdalelor sau ale gatului) cauzate de bacteria numita streptococcus pyogenes. Medicamentul se foloseste atunci cand betalactaminele nu sunt adecvate, in tarile sau regiunile in care exista un nivel ridicat de rezistenta la macrolide.
    Persoanele autorizate sa prescrie acest medicament trebuie sa ia in considerare orientarile oficiale privind utilizarea medicamentelor antibacteriene si nivelurile locale de rezistenta la antibiotice.
    Medicamentul se poate elibera numai pe baza de reteta.

    Administrare

    Doza recomandata de Ketek este de 800 mg (doua comprimate) o data pe zi. Comprimatele trebuie inghitite intregi, cu apa, cu sau fara alimente. Administrarea Ketek la culcare poate reduce impactul potential al efectelor secundare, precum tulburarile vizuale si pierderea constientei. In cazul pneumoniei, comprimatele trebuie administrate timp de sapte pana la zece zile. in cazul celorlalte infectii, medicamentul se administreaza timp de cinci zile. La pacientii cu afectiuni renale severe si anumite afectiuni hepatice poate fi necesara utilizarea unei doze mai mici. Pentru informatii suplimentare, a se consulta prospectul.

    Contraindicatii
    Ketek nu trebuie administrat persoanelor cu hipersensibilitate (alergice) la telitromicina, la oricare macrolid sau oricare alt ingredient al acestui medicament. Medicamentul nu trebuie administrat pacientilor cu miastenie gravis (o afectiune a nervilor care determina slabiciune musculara) sau care au avut hepatita (inflamatie la nivelul ficatului) sau icter dupa administrarea anterioara a telitromicinei.
    De asemenea, Ketek nu trebuie administrat la pacientii care primesc oricare din urmatoarele medicamente:
    - cisaprida (utilizata pentru a trata anumite afectiuni gastrice);
    - „derivati de alcaloizi ergotaminici”, ca de exemplu ergotamina si dihidroergotamina (utilizate pentru a trata migrenele);
    - pimozida (utilizata pentru a trata bolile psihice);
    - astemizol sau terfenadina, (utilizate frecvent pentru a trata simptomele alergice – aceste medicamente se pot elibera fara reteta);
    - simvastatina, atorvastatina sau lovastatina (utilizate pentru scaderea nivelului sanguin de colesterol).
    Ketek nu trebuie administrat la pacientii cu antecedente personale sau familiale de „sindrom de QT prelungit” sau „interval QT prelungit dobandit” (intreruperea batailor inimii). La pacientii cu afectiuni renale sau hepatice severe, Ketek nu trebuie administrat in asociere cu anumite medicamente care pot afecta metabolizarea telitromicinei, inclusiv inhibitori de proteaza (utilizati in infectia HIV) si ketokonazol (un medicament antimicotic).

    Reactii adverse
    Cel mai frecvent efect secundar asociat medicamentului Ketek (observat la mai mult de 1 din 10 pacienti) este diareea. Pentru lista completa a tuturor efectelor secundare raportate asociate cu Ketek, a se consulta prospectul.

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