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fopen(/var/www/html/sfatulmedicului.ro/magazin_plafar/system/cache/cache.currency.1414813477): failed to open stream: No such file or directory in /var/www/html/sfatulmedicului.ro/magazin_plafar/system/library/cache.php on line 36Warning: fwrite(): supplied argument is not a valid stream resource in /var/www/html/sfatulmedicului.ro/magazin_plafar/system/library/cache.php on line 38Warning: fclose(): supplied argument is not a valid stream resource in /var/www/html/sfatulmedicului.ro/magazin_plafar/system/library/cache.php on line 40 nystatin prospect
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nystatin prospect

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  • NYSTATIN, pulbere

    Compozitie
    Flacoane continand 6 g pulbere ce contine 2 400 000 UI nistatin, 1 ml de suspensie contine 120 000 UI.

    Actiune terapeutica
    Nystatin este un antibiotic polienic ce interfera (prin legarea sterolilor, in principal a ergosterolului) cu permeabilitatea membranei celulare a fungilor sensibili. Actioneaza in principal pe candida spp., dar si pe Aspergilus spp., Coccidiosides immitis, Cryptococcus neoformans, Histoplasma capsulatum, Blastomyces dermatidis.

    Indicatii
    candidoze superficiale mucoase (orala, gastrointestinala, vaginala) si cutanate. Suspensia se administreaza oral la copii si la persoanele cu leziuni oro-faringiene importante, precum si ca aplicatie locala pe piele si mucoase. Asociat cu antibiotice pentru supresia dezvoltarii exagerate a florei intestinale.

    Doze si mod de administrare
    Suspensia se prepara prin introducerea in flaconul cu pulbere a 20 ml apa distilata (2 fiole), dupa care se agita energic flaconul timp de 2-3 minute. Suspensia astfel obtinuta contine 120 000 UI Nystatin/ml. Suspensia gata preparata se utilizeaza timp de 4-6 zile daca se pastreaza la temperatura camerei si circa 10 zile daca este conservata la frigider; se agita energic flaconul inainte de fiecare intrebuintare. Pentru tratamentul candidozei esofagiene sau intestinale, se administreaza. La adulti, doze de 500 000 sau 1 000 000 UI, oral de 3-4 ori pe zi; la copii, 100 000 UI sau mai mult, oral de 3-4 ori pe zi. Pentru tratamentul leziunilor bucale, 100 000 UI de 4 ori pe zi. La nou-nascuti, se pot administra doze de 100 000 UI de maximum 4 ori pe zi. In infectiile vaginale, se administreaza de 2 ori pe zi cate 100 000-200 000 UI, in tamponament local.

    Contraindicatii
    Alergie specifica.

    Reactii adverse
    Uneori greata, voma, diaree (la doze mari), rar iritatie la aplicare locala sau intravaginal, foarte rar reactii alergice (la Nystatin sau la candidina eliberata prin distrugerea ciupercii).

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