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SONNENTOR CEAI VERDE IASOMIE 100G BUC  SONNENTOR
Sonnentor Ceai Verde Iasomie 100g Buc Sonnentor

Ceai Verde de Iasomie O specialitate de ceai clasic si indragit, cu gust fin si cu aroma placuta. Pentru crearea lui s-a folosit ceaiul verde combinat cu flori de iasomie proaspat culese; astfel ceai...


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  • Nplate

    Compozitie
    Nplate este o pulbere pentru solutie injectabila. Medicamentul contine substanta activa romiplostim.

    Indicatii
    Nplate este utilizat la adultii cu purpura trombocitopenica imuna de lunga durata, o boala in care sistemul imunitar al pacientului distruge trombocitele (componente ale sangelui care realizeaza coagularea). Pacientii cu purpura trombocitopenica imuna au un numar mic de trombocite si prezinta riscul sangerarii. Nplate este utilizat la pacientii care au fost deja tratati cu medicamente, cum ar fi corticosteroizii sau imunoglobulinele, si carora le-a fost indepartata splina, daca aceste tratamente nu au functionat. De asemenea, poate fi avut in vedere pentru utilizarea la pacientii care au fost tratati pentru purpura trombocitopenica imuna, care au splina si care nu pot fi operati. Splina este un organ implicat in distrugerea trombocitelor. Deoarece numarul pacientilor cu purpura trombocitopenica imuna este scazut, boala este considerata „rara”, iar Nplate a fost desemnat „medicament orfan” (un medicament folosit in boli rare) la 27 mai 2005. Medicamentul se poate elibera numai pe baza de reteta.

    Administrare
    Tratamentul cu Nplate trebuie supravegheat de un medic cu experienta in tratarea bolilor de sange. Nplate se administreaza o data pe saptamana, subcutanat. Doza initiala depinde de greutatea pacientului si este apoi ajustata in fiecare saptamana pentru a mentine numarul trombocitelor la nivelurile tinta. Tratamentul poate fi intrerupt daca numarul trombocitelor este prea mare. Tratamentul cu Nplate trebuie intrerupt dupa patru saptamani de tratament cu doze maxime de Nplate daca numarul trombocitelor nu atinge niveluri suficient de mari pentru a reduce riscul sangerarii. Nplate trebuie utilizat cu precautie la pacientii cu afectiuni hepatice sau renale, deoarece nu a fost studiat oficial pentru acest grup.

    Actiune terapeutica
    Substanta activa din Nplate, romiplostim, este un medicament care stimuleaza producerea de trombocite. In organism, un hormon denumit „trombopoietina” stimuleaza producerea de trombocite din maduva osoasa. Romiplostim este o proteina care a fost „modificata” (conceputa specific) pentru a se putea atasa la aceeasi receptori si pentru a-i putea stimula ca si trombopoietina. Mimand activitatea trombopoietinei, romiplostim stimuleaza producerea de trombocite, crescand numarul trombocitelor din sange. Romiplostim este produs printr-o metoda cunoscuta ca „tehnologia ADN-ului recombinant”: este sintetizata de o bacterie care a primit o gena (ADN), devenind astfel capabila sa produca romiplostim.

    Contraindicatii
    Nplate nu trebuie administrat persoanelor care pot prezenta hipersensibilitate (alergie) la romiplostim, la oricare alt ingredient sau la proteinele produse de Escherichia coli (o bacterie).

    Reactii adverse
    Cel mai frecvent efect secundar asociat cu Nplate (observat la mai mult de 1 din 10 pacienti) este cefaleea. Pentru lista completa a tuturor efectelor secundare raportate asociate cu Nplate, a se consulta prospectul.

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    Compozitie Vivace 2,5 mg, comprimate Substanta activa din Vivace 2,5 mg comprimate este ramipril. Celelalte componente sunt: hidrogenocarbonat de sodiu, lactoza monohidrat, croscarmeloza sodica, amidon pregelatinizat, stearilfumarat de sodiu, amestec colorant PB...citeste mai mult


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