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fopen(/var/www/html/sfatulmedicului.ro/magazin_plafar/system/cache/cache.currency.1414818029): failed to open stream: No such file or directory in /var/www/html/sfatulmedicului.ro/magazin_plafar/system/library/cache.php on line 36Warning: fwrite(): supplied argument is not a valid stream resource in /var/www/html/sfatulmedicului.ro/magazin_plafar/system/library/cache.php on line 38Warning: fclose(): supplied argument is not a valid stream resource in /var/www/html/sfatulmedicului.ro/magazin_plafar/system/library/cache.php on line 40 aminoglicozide
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aminoglicozide

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Cordyceps sinensis este o planta utilizata amp;icirc;n medicinaamp; traditionala chineza, ca excelent stimulator al imunitatii, potentiator al performantelor fizice si al longevitatii, energizant si ...


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  • MYOBLOC


    Toxina botulinica tip B

    Indicatii

    Tratamentul distoniei cervicale, pentru reducerea severitatii durerilor de gat si a pozitiei anormale a capului.

    Precautii

    Folositi cu precautie in bolile de neuron motor periferic (de ex. scleroza amiotrofica, neuropatia motorie), sau in afectiunile placii neuromusculare (miastenia gravis, sandromul Eaton-Lambert). Efectul in urma administrarii diferitor serotipuri de neurotoxina botulinica la in interval mai mic de 4 luni, este necunoscut; ar putea precipita paralizia neuromusculara. Nu au fost determinate siguranta si eficacitatea administrarii la copii.
    Durata efectului este intre 12-16 saptamani la o doza de 5,000-10,000 UI.
    Daca pacientul inghite o doza sau este administrata accidental o supradoza, se monitorizeaza cu atentie cateva saptamani pentru depistarea S&S de slabiciune sau paralizie. Exista o incidenta crescuta a disfagiei la doze mari administrate in muschii sternocleidomastoidieni. Incidenta xerostomiei poate creste cand se administreaza in muschiul splenius capitis, trapez, sau sternocleidomastoidian.
    Poate fi pastrata la 2-8C timp de 21 de luni. Nu congelati. Dupa diluare cu solutie salina se pastreaza maxim 4 h.
    Observatii pentru pacient – familIE: Medicamentul este folosit pentru ameliorarea contracturilor anormale ale capului si gatului, sau spasticitatea extremitatilor, permitand un control superior asupra miscarilor, posturii si activitatilor efectuate. Nu efectuati activitati ce necesita atentie sporita pana la trecerea efectelor medicamentului. Poate determina letargie. Anuntati aparitia dificultatii la deglutitie, dispneei, afectiunilor respiratorii, oboselii. Efectul dureaza de obicei 3 luni, dupa care e necesara repetarea terapiei.
    Evaluarea si controlul terapiei: Investigati antecedentele de neuropatie, boli neurologice sau neuromusculare. Nu administrati alt serotip de toxina la un interval mai mic de 4 luni.
    Interactiuni medicamentoase: Efectul toxinei botulinice poate fi potentat de aminoglicozide sau alte medicamente ce interfera cu transmiterea neuromusculara (de ex. curarizante).

    Reactii adverse

    Cele mai frecvente: xerostomie, disfagie, dispepsie, si durere la locul injectarii. gastrointestinale: greata si varsaturi, discomfort gastrointestinal, glosite, stomatite. SNC: cefalee, torticolis, migrena, anxietate, tremor, hiperestezie, somnolenta, confuzie. Respirator: rinite, dispnee, afectiuni pulmonare, pneumonie. Musculoscheletal: artralgie, miastenie, artrite. Genito-urinare: infectii urinare, cistite, candidoza vaginala. Dermatologic: prurit, echimoze. Oftalmologic: ambliopie. Otic: otita medie, tinitus. Manifestari generale: infectii, febra, frisoane, slabiciune, infectii virale. Diverse: edem periferic, hipercolesterolemie, reactii alergice, abcese, chisturi, neoplasm, vasodilatatie.

    Actiune

    Toxina botulinica. Produce paralizie flasca prin inhibarea eliberarii acetilcolinei la nivelul jonctiunii neuromusculare.

    Mod de administrare

    Injectie: Distonie cervicala: Pacientii cu istoric de toleranta la toxina botulinica, initial: 2,500-5,000 U divizate intre muschii afectati. Pacientii fara istoric de utilizare a toxinei botulinice: se foloseste doza initiala mai mica. Se individualizeaza fiecare doza in functie de pacient.

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